Hydrochlorothiazide and Cozaar are two medications utilized to treat hypertension, or high blood pressure. These medications have now been combined into one drug called Losartan potassium-hydrochlorothiazide. According to eMEDTV, this drug can lower blood pressure more than each of the tablets when taken alone.
Losartan potassium-hydrochlorothiazide, also known as Hyzaar, is administered as a prescription. It has only been approved for use in adults. Patients consume it as a once-a-day tablet.
The general effect of the medications hydrochlorothiazide and Cozaar is a relaxing of the blood vessels. This lowers blood pressure. Cozaar is an angiotensin II receptor blocker (ARB). As its moniker suggests, it works against angiotensin II receptors so that angiotensin II does not work. Because angiotensin II constricts the vessels of the blood, blocking it relaxes the vessels and lowers blood pressure.
Hydrochlorothiazide works differently. It is one of the drugs known as a “water pill” because it helps the kidneys to remove more salt and water from the blood. As blood volume goes down, so does blood pressure.
The effect of hydrochlorothiazide and Cozaar on blood pressure can be significant. In studies, it helped the systolic blood pressure to drop by up to 16 mmHg and the diastolic pressure to drop by 9 mmHg. The systolic blood pressure is the first or top number of a blood pressure reading, while the diastolic number is the second. The exact drop in blood pressure was related to the amount of hydrochlorothiazide and Cozaar one was taking.
The benefits of hydrochlorothiazide and Cozaar are numerous. High blood pressure significantly raises the risk of many serious health conditions. These include cardiovascular disease and stroke. As obesity increases, so does the number of people with hypertension, and new and stronger medications to treat high blood pressure are needed. By combining these drugs into one pill, the effect can be multiplied.
It is also advantageous for people to be able to consume the two medications in one pill. Some patients find it more convenient. Also, many people with high blood pressure do not take the medication that they need because they do not like taking so much medication. With fewer medications to take, they may be more likely to continue treatment.
There may be side effects with the combination of hydrochlorothiazide and Cozaar. Cough, back pain and dizziness are a few of the potential side effects. Other potential side effects include low blood potassium and infection.
Hydrochlorothiazide and Cozaar are two important medications in the fight against high blood pressure. Now they work together in the form of losartan potassium-hydrochlorothiazide.